Fc gamma RII (CD32) antibody

Catalog No. ABIN610037

The Mouse Monoclonal anti- antibody has been validated for FACS and Func. It is suitable to detect in samples from Human. There is 1 publication available.

Quick Overview for Fc gamma RII (CD32) antibody (ABIN610037)

Target: Fc gamma RII (CD32)

Fragment: Fab fragment

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 7-3

Product Details

Specificity: Domain 2 epitope of all CD32 isoforms. It exhibits preferential binding to Fc gRIIb (inhibitory) isoform transfectants.

Purification: Gel filtration

Sterility: Sterile filtered

Immunogen: Human K562 tumor cells and L cells transfected with human Fc gamma RII.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Blocks immune complex binding. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride. Product was sterile filtered, vialed under aseptic conditions. No preservative added

Preservative: Without preservative

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References

Barboule, Lafon, Chadebech, Vidal, Valette: "Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition." in: FEBS letters, Vol. 444, Issue 1, pp. 32-7, (1999) (PubMed).

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: FCGR2 / CD32